LymphedemaV1, Main, Exploration, bibRecord, 00EB11

The effect of coumarin (5,6 benzo-α-pyrone) on elicited members of the mononuclear system in dogs with chronic secondary lymphedema

Identifieur interne : 00EB11 ( Main/Exploration ); précédent : 00EB10; suivant : 00EB12

The effect of coumarin (5,6 benzo-α-pyrone) on elicited members of the mononuclear system in dogs with chronic secondary lymphedema

Auteurs : N. B. Piller [Australie] ; L. Clodius [Suisse]

Source :

Research in Experimental Medicine [ 0300-9130 ] ; 1986-03-01.

RBID : ISTEX:E0CDC72A75F291E7A4931F667EDB318A95393335

Descripteurs français

KwdFr :
- Animaux, Chiens, Coumarines (pharmacologie), Lymphoedème (), Lymphoedème (sang), Maladie chronique, Monocytes (), Phagocytose.
MESH :
- pharmacologie : Coumarines.
- sang : Lymphoedème.
Pascal (Inist)
- Activité biologique, Animal, Animaux, Chien, Chiens, Coumarine dérivé, Inflammation, Lymphoedème, Macrophage, Maladie chronique, Monocytes, Mononucléaire, Phagocytose.

English descriptors

KwdEn :
- Animal, Animals, Biological activity, Chronic Disease, Coumarine derivatives, Coumarins (pharmacology), Dog, Dogs, Inflammation, Lymphedema, Lymphedema (blood), Lymphedema (complications), Macrophage, Monocytes (drug effects), Mononuclear cell, Phagocytosis.
MESH :
- chemical , pharmacology : Coumarins.
- blood : Lymphedema.
- complications : Lymphedema.
- drug effects : Monocytes.
- Animals, Chronic Disease, Dogs, Phagocytosis.

Abstract

Summary: The effect of coumarin is investigated on the morphological features of members of the mononuclear phagocytic system (MPS) attaching to subcutaneously (s.c.) implanted coverslips in “normal” and chronically lymphedematous tissues. In untreated “normal” tissues there was no attachment suggesting that the presence of lymphedema elsewhere influences MPS activity. Coumarin restored attachment proportions to those found in normal tissues of dogs with no lymphedema. In lymphedema, coumarin significantly increased the proportion of macrophages which were round with less than ten pseudopods (new recruits) and the proportion with distinct pseudopods combined with more than ten vacuoles (active elicited members of the MPS). Coumarin resulted in a significant decline in the proportion of macrophages which were round and with more than ten apparently lipid-containing vacuoles, suggesting a facilitation of their removal to other sites.

Url:

https://api.istex.fr/document/E0CDC72A75F291E7A4931F667EDB318A95393335/fulltext/pdf

DOI: 10.1007/BF01851991

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Summary: The effect of coumarin is investigated on the morphological features of members of the mononuclear phagocytic system (MPS) attaching to subcutaneously (s.c.) implanted coverslips in “normal” and chronically lymphedematous tissues. In untreated “normal” tissues there was no attachment suggesting that the presence of lymphedema elsewhere influences MPS activity. Coumarin restored attachment proportions to those found in normal tissues of dogs with no lymphedema. In lymphedema, coumarin significantly increased the proportion of macrophages which were round with less than ten pseudopods (new recruits) and the proportion with distinct pseudopods combined with more than ten vacuoles (active elicited members of the MPS). Coumarin resulted in a significant decline in the proportion of macrophages which were round and with more than ten apparently lipid-containing vacuoles, suggesting a facilitation of their removal to other sites.</div>
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The effect of coumarin (5,6 benzo-α-pyrone) on elicited members of the mononuclear system in dogs with chronic secondary lymphedema

The effect of coumarin (5,6 benzo-α-pyrone) on elicited members of the mononuclear system in dogs with chronic secondary lymphedema

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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